RRC ID 68200
著者 Buffalo V.
タイトル Quantifying the relationship between genetic diversity and population size suggests natural selection cannot explain Lewontin's Paradox.
ジャーナル Elife
Abstract Neutral theory predicts that genetic diversity increases with population size, yet observed levels of diversity across metazoans vary only two orders of magnitude while population sizes vary over several. This unexpectedly narrow range of diversity is known as Lewontin's Paradox of Variation (1974). While some have suggested selection constrains diversity, tests of this hypothesis seem to fall short. Here, I revisit Lewontin's Paradox to assess whether current models of linked selection are capable of reducing diversity to this extent. To quantify the discrepancy between pairwise diversity and census population sizes across species, I combine previously-published estimates of pairwise diversity from 172 metazoan taxa with newly derived estimates of census sizes. Using phylogenetic comparative methods, I show this relationship is significant accounting for phylogeny, but with high phylogenetic signal and evidence that some lineages experience shifts in the evolutionary rate of diversity deep in the past. Additionally, I find a negative relationship between recombination map length and census size, suggesting abundant species have less recombination and experience greater reductions in diversity due to linked selection. However, I show that even assuming strong and abundant selection, models of linked selection are unlikely to explain the observed relationship between diversity and census sizes across species.
巻・号 10
公開日 2021-8-19
DOI 10.7554/eLife.67509
PII 67509
PMID 34409937
PMC PMC8486380
MeSH Animals Biological Evolution Genetic Variation* Genetics, Population Phylogeny Population Density* Selection, Genetic
IF 7.08
リソース情報
GBIF Insect specimens of Iwate Prefectural Museum Insect specimens of Toyota City Nature Sanctuary Asia-Pacific Dataset Hymenoptera specimen database of Kyushu University Echinoderm collection of National Museum of Nature and Science Spermatophyta Specimens of Kawasaki Municipal Science Museum The Masayo Kato Insect Collection (Hymenoptera) of The University Museum, The University of Tokyo Invertebrate specimens (except for arthropods and mollusca) of Natural History Museum, Kishiwada City Echinodermata Specimens of the Yamagata Prefectural Museum Plant Specimen Database of Tama Forest Science Garden, Forestry and Forest Products Research Institute, Japan Insect specimens of Obihiro Centennial City Museum Marine Biological Sample Database, JAMSTEC Plant specimens of Otaru Museum Insect specimen database of Kanagawa Prefectural Museum of Natural History Arthropod specimens of Natural History Museum, Kishiwada City Herpetological specimens of Okinawa Prefectural Museum & Art Museum Crustacean collection of the National Museum of Nature and Science Insect specimens of Natural History Museum, Kishiwada City Captive Primate Specimens of Japan Monkey Centre Plant specimens of Komatsu City Museum Butterfly Specimens of Yamaguchi Prefectural Yamaguchi Museum Kyushu University Museum Coleoptera Collection Insect Specimens of the Yamagata Prefectural Museum Insect specimens of Sugadaira Montane Research Center, University of Tsukuba Insect specimens of Bihoro Museum Insect specimens of Yonezawa Insectarium Insect Specimens of Ibaraki University (Faculty of Science) Amphibian specimens of Kanagawa Prefectural Museum of Natural History Invertebrate collection of the Seto Marine Biological Laboratory, Kyoto University Bird specimens of Natural History Museum, Kishiwada City Biological Resource Center, Department of Biotechnology, National Institute of Technology and Evaluation Plant specimens of Ishikawa Museum of Natural History Crustacean Specimens of the Yamagata Prefectural Museum Mollusca collection of National Museum of Nature and Science Mollusca specimens of Okinawa Prefectural Museum & Art Museum Fungi specimens of Saitama Museum of Natural History Cnidaria specimens of Ryukyu University Museum (Fujukan) Insect specimens of Himeji City Science Museum Plant Specimens of The Cattle Museum Arthropoda Collection of the Seto Marine Biological Laboratory, Kyoto University Long-term fauna and flora records of the experimental forests of the Forest Research Station of Hokkaido University, Japan Spermatophyte collection of Himeji City Science Museum Fish Specimens of the Yamagata Prefectural Museum Chromista Collection of the Seto Marine Biological Laboratory, Kyoto University Bird specimens of Okinawa Prefectural Museum & Art Museum Birds collection of Abiko City Museum of Birds Plant specimens of Toyota City Nature Sanctuary Bird specimens of the Yamashina Institute for Ornithology Plant specimens of Tochigi Prefectural Museum Mollusca specimens of Oiso Municipal Museum Mammal specimens of Okinawa Prefectural Museum & Art Museum Algae collection of Museum of Natural and Environmental History, Shizuoka Plant specimens of Nasunogahara Museum Avian Specimens of the Yamagata Prefectural Museum Shallow-water fauna of Sagami Bay Insect specimens of Okinawa Prefectural Museum & Art Museum Insect specimens of Otaru Museum Plant specimens of Horaiji-san Museum of Natural History Toji K. collection Insect specimens of Kaizuka City Museum of Natural History Mammalian Specimens of the Yamagata Prefectural Museum Fish specimens of Bihoro Museum Reptile specimens of Kanagawa Prefectural Museum of Natural History Insect specimens of Rikuzen-Takata City Museum The 6-7th National Survey on the Natural Environment: Vegetation Survey Mammal assemblages recorded by camera traps inside and outside the evacuation zone of the Fukushima Daiichi Nuclear Power Plant accident Vascular Plant Specimens of Yamagata Prefectural Museum Nagoya-Plants Mammal 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Kagoshima Prefectural Museum Vascular plants collection of Hiratsuka City Museum Insecta collection of Museum of Natural and Environmental History, Shizuoka Plant specimens of Kushiro City Museum Dry specimens of Recent Mollusca in the Department of Historical Geology and Paleontology, The University Museum, The University of Tokyo (UMUT) Mollusca specimens of Ryukyu University Museum (Fujukan) Bird specimens of Komatsu City Museum Insect specimens of Nasunogahara Museum Fish specimens of Takatsuki Nature Museum (Aquapia Akutagawa) Monitoring records of plant species in the Hakone region of Fuji-Hakone-Izu National Park, Japan, 2001-2010 Mammal specimens of Takatsuki Nature Museum (Aquapia Akutagawa) Plant specimens of Horaiji-san Museum of Natural History Kichi T. collection Protochordata collection of National Museum of Nature and Science Annual Census on Waterfowl (Anatidae) Population The Suguru Igarashi Insect Collection (Lepidoptera: Hesperiidae) of The University Museum, The 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Records of Japan Vascular plant specimens of Iida City Museum Bird specimens of Ryukyu University Museum (Fujukan) Bird Specimens of The Cattle Museum Mammal specimens of Saitama Museum of Natural History Botanical Specimens of Kaizuka City Museum of Natural History (KCMN) AIS Wildtype Populations of Arabidopsis Insect collection of Biodiversity Center of Japan, Ministry of the Environment Molluscan specimens of Bihoro Museum Hymenoptera Specimens of Yamaguchi prefectural Yamaguchi Museum Plankton&BenthosResearch Tracheophyta collection of Biodiversity Center of Japan, Ministry of the Environment Mollusca specimens of Wakayama Prefectural Museum of Natural History Vascular plant specimens of The Shirakami Research Center for Environmental Sciences, Hirosaki University Vascular plant specimens of Aomori City Forestry Museum Bird specimens of Tochigi Prefectural Museum Insect specimens of Oiso Municipal Museum Asahikawa Educational College herbarium Plant specimens of Oiso Municipal Museum Plant specimens of the Museum of Yamagata University Mollusk Collection of Yokosuka City Museum Plant specimens of Toyota City Nature Sanctuary (from non-museum circle) Fungal Collection of Natural History Museum and Institute, Chiba Vascular plant specimens of Toyama Science Museum Birds Specimens of Akita Prefectural Museum Crustacean specimens of Kaizuka City Museum of Natural History Insect specimens of Komatsu City Museum Mollusca specimens of Kuroshio Biological Research Foundation Insect specimens of Toyama Science Museum Herbarium of Hokkaido University Museum (SAPS) Plant specimens of Takatsuki Nature Museum (Aquapia Akutagawa) Crustacea specimens of Toyama Science Museum Ascidians Specimens of Akita Prefectural Museum Fish collection of the Kagoshima University Museum Echinoderms Specimens of Akita Prefectural Museum Actinopterygius Specimens of Akita Prefectural Museum Vascular Plant Collection of Natural History Museum and Institute, Chiba Herbarium Specimens of Museum of Nature and Human Activities, Hyogo Pref., Japan Insect Collection of Saitama Museum of Natural History Mammalians Specimens of Akita Prefectural Museum Marine specimens of Misaki Marine Biological Station, Graduate School of Science, The University of Tokyo Malacostracans Specimens of Akita Prefectural Museum Molluscus specimens of Toyohashi Museum of Natural History Ibaraki Nature Museum, Arthropoda collection Ibaraki Nature Museum, Mollusk collection Spermatophyta collection of Museum of Natural and Environmental History, Shizuoka Ibaraki Nature Museum, Mammals collection Ibaraki Nature Museum, Fish collection Ibaraki Nature Museum, Birds collection Ibaraki Nature Museum, Amphibians and Reptiles collection Ibaraki Nature Museum, Algae collection Shellfish specimens of the Nishinomiya Shell Museum, Japan Fish collection of the Museum of Nature and Human Activities, Hyogo Benthos collection of the Museum of Nature and Human Activities, Hyogo Akita Prefectural Museum, Observation Records of Birds in Akita Prefecture Ibaraki Nature Museum, Vascular Plants collection Japan Collection of Microorganisms, RIKEN BioResource Center Fish Collection of Yokosuka City Museum Fish Collection of Hokkaido University Macroalgal collection of National Museum of Nature and Science (TNS) Vascular plant specimens of National Museum of Nature and Science (TNS) Insect specimens of Kashihara City Museum of Insect Plant Specimens of Kurashiki Museum of Natural History Herbarium Specimens of Tokushima Prefectural Museum, Japan Fish Specimens of Tokushima Prefectural Museum, Japan Insect Specimen Database of Fukui City Museum of Natural History Insect specimens of Omogo Mountain Museum Fish Specimens of Graduate School of Bioresources Mie University Osaka Prefectural Minoh Park Insects Museum Herbarium of Kitakyushu Museum of Natural History and Human History Fish specimen database of Osaka Museum of Natural History Hymenopteran specimen database of Osaka Museum of Natural History Fish collection of National Museum of Nature and Science Bird collection of National Museum of Nature and Science Mammal collection of National Museum of Nature and Science Freshwater Fish Specimens of Lake Biwa Museum Fish Collection of Natural History Museum and Institute, Chiba Plant Specimens of Lake Biwa Museum Spermatophyta specimens of Iwate Prefectural Museum Rust fungus specimen of Research Group of Plant Parasitic Mycology, Faculty of Life and Environmental Sciences, University of Tsukuba Herpetological collection of National Museum of Nature and Science Fish Collection of Kanagawa Prefectural Museum of Natural History Vascular Plants Collection of Sagamihara City Museum Mollusca collection, Museum of Natural and Environmental History, Shizuoka Plant specimens in the Museum of Nature and Human Activities, Hyogo Prefecture, Japan Insect specimens in the Museum of Nature and Human Activities, Hyogo Prefecture, Japan Freshwater Fish specimens of Taga Town Museum, Shiga Pref., Japan Freshwater shellfish specimens of Taga Town Museum, Shiga Pref., Japan Mammals specimens of Taga Town Museum, Shiga Pref., Japan Insect specimens of Taga Town Museum, Shiga Pref., Japan Plant specimens of Taga Town Museum, Shiga Pref., Japan Lepidoptera specimen database of Osaka Museum of Natural History Arthropoda (excepting insect) collection of Osaka Museum of Natural History Invertebrate (minor phyla) collection of Osaka Museum of Natural History Molluscan collection of Osaka Museum of Natural History Plant specimens deposited in Osaka Museum of Natural History, Japan Insect collection of Itami City Museum of Insects Vascular Plant Specimens of Kochi Prefectural Makino Botanical Garden Zoological specimens of Gifu Prefectural Museum Plant Specimens of The Shimane Nature Museum of Mt. 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