| RRC ID |
68593
|
| 著者 |
Kobayashi S, Ohgoe Y, Ozeki K, Hirakuri K, Aoki H.
|
| タイトル |
Dissolution effect and cytotoxicity of diamond-like carbon coatings on orthodontic archwires.
|
| ジャーナル |
J Mater Sci Mater Med
|
| Abstract |
Nickel-titanium (NiTi) has been used for implants in orthodontics due to the unique properties such as shape memory effect and superelasticity. However, NiTi alloys are eroded in the oral cavity because they are immersed by saliva with enzymolysis. Their reactions lead corrosion and nickel release into the body. The higher concentrations of Ni release may generate harmful reactions. Ni release causes allergenic, toxic and carcinogenic reactions. It is well known that diamond-like carbon (DLC) films have excellent properties, such as extreme hardness, low friction coefficients, high wear resistance. In addition, DLC film has many other superior properties as a protective coating for biomedical applications such as biocompatibility and chemical inertness. Therefore, DLC film has received enormous attention as a biocompatible coating. In this study, DLC film coated NiTi orthodontic archwires to protect Ni release into the oral cavity. Each wire was immersed in physiological saline at the temperature 37 degrees C for 6 months. The release concentration of Ni ions was detected using microwave induced plasma mass spectrometry (MIP-MS) with the resolution of ppb level. The toxic effect of Ni release was studied the cell growth using squamous carcinoma cells. These cells were seeded in 24 well culture plates and materials were immersed in each well directly. The concentration of Ni ions in the solutions had been reduced one-sixth by DLC films when compared with non-coated wire. This study indicated that DLC films have the protective effect of the diffusion and the non-cytotoxicity in corrosive environment.
|
| 巻・号 |
18(12)
|
| ページ |
2263-8
|
| 公開日 |
2007-12-1
|
| DOI |
10.1007/s10856-007-3118-2
|
| PMID |
17562139
|
| MeSH |
Carbon / adverse effects
Carbon / chemistry*
Carcinoma, Squamous Cell / pathology
Coated Materials, Biocompatible / adverse effects
Coated Materials, Biocompatible / chemical synthesis*
Coated Materials, Biocompatible / chemistry
Corrosion
Diamond / adverse effects
Diamond / chemistry*
Hardness
Humans
Materials Testing
Mechanics
Models, Biological
Mouth Neoplasms / pathology
Nickel / chemistry*
Orthodontic Wires* / adverse effects
Surface Properties
Titanium / chemistry*
Toothbrushing / adverse effects
Tumor Cells, Cultured
|
| IF |
2.489
|
| リソース情報 |
| ヒト・動物細胞 |
Sa3(RCB0980) |
