| RRC ID |
69007
|
| 著者 |
Kawabata K, Totani M, Kawaguchi D, Matsuno H, Tanaka K.
|
| タイトル |
Two-Dimensional Cellular Patterning on a Polymer Film Based on Interfacial Stiffness.
|
| ジャーナル |
Langmuir
|
| Abstract |
The mechanical properties in the outermost region of a polymer film strongly affect various material functions. We here propose a novel and promising strategy for the two-dimensional regulation of the mechanical properties of a polymer film at the water interface based on an inkjet drawing of silica nanoparticles (SNPs) underneath it. A film of poly(2-hydroxyethyl methacrylate) (PHEMA), which exhibits excellent bioinertness properties at the water interface, was well fabricated on a substrate with a pattern of SNPs. X-ray photoelectron spectroscopy and atomic force microscopy confirmed that the surface of the PHEMA film was flat and chemically homogeneous. However, the film surface was in-plane heterogeneous in stiffness due to the presence of the underlying SNP lines. It was also noted that NIH/3T3 fibroblast cells selectively adhered and formed aggregates on the areas under which an SNP line was drawn.
|
| 巻・号 |
37(51)
|
| ページ |
14911-14919
|
| 公開日 |
2021-12-28
|
| DOI |
10.1021/acs.langmuir.1c02776
|
| PMID |
34902971
|
| MeSH |
Microscopy, Atomic Force
Photoelectron Spectroscopy
Polyhydroxyethyl Methacrylate*
Water*
|
| IF |
3.557
|
| リソース情報 |
| ヒト・動物細胞 |
NIH/3T3(RCB2767) |
