| RRC ID |
69781
|
| Author |
Fujita T, Lin J, Kimishima A, Arai M, Takikawa H, Ogura Y.
|
| Title |
Synthesis and biological evaluation of cajaninstilbene acid and amorfrutins A-D as cytotoxic agents against human pancreatic carcinoma PANC-1 cells.
|
| Journal |
Biosci Biotechnol Biochem
|
| Abstract |
A concise synthesis of cajaninstilbene acid was achieved in seven steps from (E)-3,5-dimethoxystilbene in 8.6% overall yield via the Claisen rearrangement of an aryl reverse-prenyl ether as the key step. Cytotoxic activities against human pancreatic carcinoma PANC-1 cells of cajaninstilbene acid and amorfrutins A-D were also evaluated.
|
| Volume |
86(5)
|
| Pages |
590-595
|
| Published |
2022-4-21
|
| DOI |
10.1093/bbb/zbac025
|
| PII |
6528368
|
| PMID |
35157035
|
| MeSH |
Cytotoxins*
Humans
Pancreatic Neoplasms
Salicylates
Stilbenes* / pharmacology
|
| IF |
1.516
|
| Resource |
| Human and Animal Cells |
PANC-1(RCB2095) |
