| RRC ID |
69845
|
| Author |
Mesihovic A, Ullrich S, Rosenkranz RRE, Gebhardt P, Bublak D, Eich H, Weber D, Berberich T, Scharf KD, Schleiff E, Fragkostefanakis S.
|
| Title |
HsfA7 coordinates the transition from mild to strong heat stress response by controlling the activity of the master regulator HsfA1a in tomato.
|
| Journal |
Cell Rep
|
| Abstract |
Plants respond to higher temperatures by the action of heat stress (HS) transcription factors (Hsfs), which control the onset, early response, and long-term acclimation to HS. Members of the HsfA1 subfamily, such as tomato HsfA1a, are the central regulators of HS response, and their activity is fine-tuned by other Hsfs. We identify tomato HsfA7 as capacitor of HsfA1a during the early HS response. Upon a mild temperature increase, HsfA7 is induced in an HsfA1a-dependent manner. The subsequent interaction of the two Hsfs prevents the stabilization of HsfA1a resulting in a negative feedback mechanism. Under prolonged or severe HS, HsfA1a and HsfA7 complexes stimulate the induction of genes required for thermotolerance. Therefore, HsfA7 exhibits a co-repressor mode at mild HS by regulating HsfA1a abundance to moderate the upregulation of HS-responsive genes. HsfA7 undergoes a temperature-dependent transition toward a co-activator of HsfA1a to enhance the acquired thermotolerance capacity of tomato plants.
|
| Volume |
38(2)
|
| Pages |
110224
|
| Published |
2022-1-11
|
| DOI |
10.1016/j.celrep.2021.110224
|
| PII |
S2211-1247(21)01728-9
|
| PMID |
35021091
|
| MeSH |
Acclimatization
Arabidopsis
Arabidopsis Proteins / genetics
Arabidopsis Proteins / metabolism
DNA-Binding Proteins / metabolism
Gene Expression / genetics
Gene Expression Regulation, Plant / genetics
Heat Shock Transcription Factors / genetics*
Heat Shock Transcription Factors / metabolism
Heat-Shock Proteins / metabolism
Heat-Shock Response / genetics
Hot Temperature
Plant Proteins / genetics
Plants, Genetically Modified / metabolism
Solanum lycopersicum / genetics*
Solanum lycopersicum / metabolism
Thermotolerance / genetics
Trans-Activators / genetics*
Trans-Activators / metabolism
Transcription Factors / metabolism
|
| IF |
8.109
|
| Resource |
| Arabidopsis / Cultured plant cells, genes |
rpc00046 |
