Reference - Detail
| RRC ID | 7002 |
|---|---|
| Author | Yamauchi N. |
| Title | The pathway of leucine to mevalonate in halophilic archaea: efficient incorporation of leucine into isoprenoidal lipid with the involvement of isovaleryl-CoA dehydrogenase in Halobacterium salinarum. |
| Journal | Biosci Biotechnol Biochem |
| Abstract |
The pathway of leucine to mevalonate, which has attracted attention in the study of the biosynthesis of isoprenoid in parasitic protozoa and myxobacterium, was observed in the biosynthesis of the lipid core in halophilic archaea. The involvement of isovaleryl-CoA dehydrogenase was strongly suggested, with stereospecific conversion of the diastereotopic methyl group of leucine to isoprenoidal lipid. |
| Volume | 74(2) |
| Pages | 443-6 |
| Published | 2010-1-1 |
| DOI | 10.1271/bbb.90814 |
| PII | JST.JSTAGE/bbb/90814 |
| PMID | 20139592 |
| MeSH | Halobacteriales / genetics Halobacteriales / metabolism* Halobacterium salinarum / genetics Halobacterium salinarum / metabolism* Isovaleryl-CoA Dehydrogenase / genetics Isovaleryl-CoA Dehydrogenase / metabolism* Leucine / genetics Leucine / metabolism* Lipids / genetics Mevalonic Acid / metabolism* |
| IF | 1.516 |
| Times Cited | 6 |
| WOS Category | FOOD SCIENCE & TECHNOLOGY CHEMISTRY, APPLIED BIOTECHNOLOGY & APPLIED MICROBIOLOGY BIOCHEMISTRY & MOLECULAR BIOLOGY |
| Resource | |
| General Microbes | JCM 9120 |