RRC ID |
70801
|
著者 |
Choe CP, Choi SY, Kee Y, Kim MJ, Kim SH, Lee Y, Park HC, Ro H.
|
タイトル |
Transgenic fluorescent zebrafish lines that have revolutionized biomedical research.
|
ジャーナル |
Lab Anim Res
|
Abstract |
Since its debut in the biomedical research fields in 1981, zebrafish have been used as a vertebrate model organism in more than 40,000 biomedical research studies. Especially useful are zebrafish lines expressing fluorescent proteins in a molecule, intracellular organelle, cell or tissue specific manner because they allow the visualization and tracking of molecules, intracellular organelles, cells or tissues of interest in real time and in vivo. In this review, we summarize representative transgenic fluorescent zebrafish lines that have revolutionized biomedical research on signal transduction, the craniofacial skeletal system, the hematopoietic system, the nervous system, the urogenital system, the digestive system and intracellular organelles.
|
巻・号 |
37(1)
|
ページ |
26
|
公開日 |
2021-9-8
|
DOI |
10.1186/s42826-021-00103-2
|
PII |
10.1186/s42826-021-00103-2
|
PMID |
34496973
|
PMC |
PMC8424172
|
リソース情報 |
ゼブラフィッシュ |
Tg(brn3a-hsp70:GFP )rw0110b
Tg(dao:GAL4VP16)rw0148a
Tg(HuC:Kaede)rw0130a
Tg(UAS:nfsB-mCherry)rw0144 |