Reference - Detail
| RRC ID | 70900 |
|---|---|
| Author | Miura Y, Kojima Y, Seto H, Hoshino Y. |
| Title | Bio-inert Properties of TEG Modified Dendrimer Interface. |
| Journal | Anal Sci |
| Abstract |
The bioinert interfaces that prevent adhesion of proteins and cells are important for biomaterial applications. In order to design a bioinert interface, the immobilization of an appropriate functional group and the control of molecular density is required. Dendrimer was modified with triethylene glycol (TEG) to display a dense brush structure. TEG with different density and terminal groups were immobilized with a dendrimer template and thiol terminated molecules. The inhibitory effect on protein and bacteria binding was investigated. The physical property of the interface was measured by QCM-admittance to clarify the factor of the bioinert property. |
| Volume | 37(3) |
| Pages | 519-523 |
| Published | 2021-3-10 |
| DOI | 10.2116/analsci.20P388 |
| PII | 10.2116/analsci.20P388 |
| PMID | 33310990 |
| MeSH | Bacterial Adhesion / drug effects Dendrimers / chemistry Dendrimers / pharmacology* Escherichia coli / drug effects* Microbial Sensitivity Tests Molecular Structure Polyethylene Glycols / chemistry Polyethylene Glycols / pharmacology* Staphylococcus epidermidis / drug effects* |
| Resource | |
| General Microbes | JCM2414 |