論文 - 詳細
| RRC ID | 71005 |
|---|---|
| 著者 | Ghosh K, Choi Y, Lee JW, Baraki H, Kim KP. |
| タイトル | Complete nucleotide sequence analysis and identification of 7-cyano-7-deazaguanine (PreQ0) biosynthesis-related genes in the novel Bacillus subtilis-infecting Siphoviridae family phage BSP7. |
| ジャーナル | Arch Virol |
| Abstract |
In this study, bacteriophage BSP7, a novel Bacillus subtilis-infecting member of the family Siphoviridae, was isolated from a Korean soybean-based fermented food, Deonjang, using B. subtilis ATCC 21336 as a host. The genome is 55,455 bp long with 39.92% G+C content. A total of 70 ORFs with no tRNA were detected in the genome. A distinct feature of the BSP7 genome among B. subtilis-infecting Siphoviridae family phages is the presence of putative ORFs related to biosynthesis of 7-cyano-7-deazaguanine (PreQ0), a precursor of queuosine and archaeosine biosynthesis. Bioinformatic analysis revealed that the genome of BSP7 does not exhibit any significant similarities to other phages with sequences in the NCBI database. A comparative genomic analysis also confirmed the uniqueness of BSP7 within the family Siphoviridae. |
| 巻・号 | 166(6) |
| ページ | 1795-1799 |
| 公開日 | 2021-6-1 |
| DOI | 10.1007/s00705-021-05056-4 |
| PII | 10.1007/s00705-021-05056-4 |
| PMID | 33839920 |
| MeSH | Bacillus subtilis / virology* Base Sequence DNA, Viral / genetics Gene Expression Regulation, Viral / physiology Genome, Viral* Guanine / analogs & derivatives* Guanine / biosynthesis Siphoviridae / genetics* Siphoviridae / isolation & purification Viral Proteins / genetics Viral Proteins / metabolism |
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| 一般微生物 | JCM2506 JCM2502 JCM2152 JCM2508 |