RRC ID 71372
著者 Sato Y, Atarashi K, Plichta DR, Arai Y, Sasajima S, Kearney SM, Suda W, Takeshita K, Sasaki T, Okamoto S, Skelly AN, Okamura Y, Vlamakis H, Li Y, Tanoue T, Takei H, Nittono H, Narushima S, Irie J, Itoh H, Moriya K, Sugiura Y, Suematsu M, Moritoki N, Shibata S, Littman DR, Fischbach MA, Uwamino Y, Inoue T, Honda A, Hattori M, Murai T, Xavier RJ, Hirose N, Honda K.
タイトル Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians.
ジャーナル Nature
巻・号 599(7885)
ページ 458-464
公開日 2021-11-1
DOI 10.1038/s41586-021-03832-5
PII 10.1038/s41586-021-03832-5
PMID 34325466
MeSH 3-Hydroxysteroid Dehydrogenases / metabolism Aged, 80 and over Animals Anti-Bacterial Agents / biosynthesis Anti-Bacterial Agents / metabolism Bacteria / classification Bacteria / enzymology Bacteria / isolation & purification Bacteria / metabolism* Biosynthetic Pathways* Centenarians* Cholestenone 5 alpha-Reductase / metabolism Feces / chemistry Feces / microbiology Female Gastrointestinal Microbiome* Gram-Positive Bacteria / metabolism Humans Lithocholic Acid / analogs & derivatives* Lithocholic Acid / biosynthesis* Lithocholic Acid / metabolism Male Mice Symbiosis
リソース情報
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