RRC ID 71589
Author Davison HR, Pilgrim J, Wybouw N, Parker J, Pirro S, Hunter-Barnett S, Campbell PM, Blow F, Darby AC, Hurst GDD, Siozios S.
Title Genomic diversity across the Rickettsia and 'Candidatus Megaira' genera and proposal of genus status for the Torix group.
Journal Nat Commun
Abstract Members of the bacterial genus Rickettsia were originally identified as causative agents of vector-borne diseases in mammals. However, many Rickettsia species are arthropod symbionts and close relatives of ‘Candidatus Megaira’, which are symbiotic associates of microeukaryotes. Here, we clarify the evolutionary relationships between these organisms by assembling 26 genomes of Rickettsia species from understudied groups, including the Torix group, and two genomes of ‘Ca. Megaira’ from various insects and microeukaryotes. Our analyses of the new genomes, in comparison with previously described ones, indicate that the accessory genome diversity and broad host range of Torix Rickettsia are comparable to those of all other Rickettsia combined. Therefore, the Torix clade may play unrecognized roles in invertebrate biology and physiology. We argue this clade should be given its own genus status, for which we propose the name ‘Candidatus Tisiphia’.
Volume 13(1)
Pages 2630
Published 2022-5-12
DOI 10.1038/s41467-022-30385-6
PII 10.1038/s41467-022-30385-6
PMID 35551207
PMC PMC9098888
MeSH Animals Arthropods* Genomics Mammals Phylogeny Rickettsia* / genetics Symbiosis / genetics
IF 12.121
Algae NIES-296 NIES-425