RRC ID 71792
Author Matsunami K, Otsuka H, Kondo K, Shinzato T, Kawahata M, Yamaguchi K, Takeda Y.
Title Absolute configuration of (+)-pinoresinol 4-O-[6''-O-galloyl]-beta-D-glucopyranoside, macarangiosides E, and F isolated from the leaves of Macaranga tanarius.
Journal Phytochemistry
Abstract A lignan glucoside, (+)-pinoresinol 4-O-[6''-O-galloyl]-beta-D-glucopyranoside (1), and two megastigmane glucosides, named macarangiosides E and F (2,3), together with 15 known compounds (4-18) were isolated from leaves of Macaranga tanarius (L.) Müll.-Arg. (Euphorbiaceae). Their structures were elucidated by spectroscopic and chemical analyses. In addition, the absolute stereochemistry of macarangiosides B and C isolated previously from the same plant was also determined for the first time. Compounds 1 and 2 were galloylated on glucose and possessed potent DPPH radical-scavenging activity.
Volume 70(10)
Pages 1277-85
Published 2009-7-1
DOI 10.1016/j.phytochem.2009.07.020
PII S0031-9422(09)00284-2
PMID 19683319
MeSH Cell Line, Tumor Cell Survival / drug effects Cyclohexanones / chemistry Cyclohexanones / pharmacology Euphorbiaceae / chemistry* Free Radical Scavengers / chemistry Free Radical Scavengers / pharmacology* Glucosides / chemistry* Glucosides / pharmacology* Humans Molecular Structure Norisoprenoids / chemistry Norisoprenoids / pharmacology Plant Leaves / chemistry*
IF 3.044
Human and Animal Cells A549(RCB0098)