RRC ID |
71792
|
著者 |
Matsunami K, Otsuka H, Kondo K, Shinzato T, Kawahata M, Yamaguchi K, Takeda Y.
|
タイトル |
Absolute configuration of (+)-pinoresinol 4-O-[6''-O-galloyl]-beta-D-glucopyranoside, macarangiosides E, and F isolated from the leaves of Macaranga tanarius.
|
ジャーナル |
Phytochemistry
|
Abstract |
A lignan glucoside, (+)-pinoresinol 4-O-[6''-O-galloyl]-beta-D-glucopyranoside (1), and two megastigmane glucosides, named macarangiosides E and F (2,3), together with 15 known compounds (4-18) were isolated from leaves of Macaranga tanarius (L.) Müll.-Arg. (Euphorbiaceae). Their structures were elucidated by spectroscopic and chemical analyses. In addition, the absolute stereochemistry of macarangiosides B and C isolated previously from the same plant was also determined for the first time. Compounds 1 and 2 were galloylated on glucose and possessed potent DPPH radical-scavenging activity.
|
巻・号 |
70(10)
|
ページ |
1277-85
|
公開日 |
2009-7-1
|
DOI |
10.1016/j.phytochem.2009.07.020
|
PII |
S0031-9422(09)00284-2
|
PMID |
19683319
|
MeSH |
Cell Line, Tumor
Cell Survival / drug effects
Cyclohexanones / chemistry
Cyclohexanones / pharmacology
Euphorbiaceae / chemistry*
Free Radical Scavengers / chemistry
Free Radical Scavengers / pharmacology*
Glucosides / chemistry*
Glucosides / pharmacology*
Humans
Molecular Structure
Norisoprenoids / chemistry
Norisoprenoids / pharmacology
Plant Leaves / chemistry*
|
IF |
3.044
|
リソース情報 |
ヒト・動物細胞 |
A549(RCB0098) |