| RRC ID |
71927
|
| Author |
Zou K, Zhu S, Meselhy MR, Tohda C, Cai S, Komatsu K.
|
| Title |
Dammarane-type Saponins from Panax japonicus and their neurite outgrowth activity in SK-N-SH cells.
|
| Journal |
J Nat Prod
|
| Abstract |
Four new dammarane-type saponins (1-4), named yesanchinosides G-J, together with nine ginsenosides (5-13) were isolated from Ye-Sanchi, the underground part of Panax japonicus collected in the south of Yunnan Province, China. Their structures were elucidated on the basis of spectroscopic and chemical methods. Ginsenosides Rb(1) and Rb(3) and notoginsenosides R(4) (6) and Fa (7) showed significant neurite outgrowth enhancing activities in human neuroblastoma SK-N-SH cells.
|
| Volume |
65(9)
|
| Pages |
1288-92
|
| Published |
2002-9-1
|
| DOI |
10.1021/np0201117
|
| PII |
np0201117
|
| PMID |
12350149
|
| MeSH |
Drugs, Chinese Herbal / chemistry*
Ginsenosides / chemistry
Ginsenosides / isolation & purification*
Ginsenosides / pharmacology
Humans
Methanol
Neurites / drug effects
Neuroblastoma
Nuclear Magnetic Resonance, Biomolecular
Panax / chemistry*
Plants, Medicinal / chemistry*
Saponins / chemistry
Saponins / isolation & purification*
Saponins / pharmacology
Stereoisomerism
Tumor Cells, Cultured / drug effects
|
| IF |
3.782
|
| Resource |
| Human and Animal Cells |
SK-N-SH(RCB0426) |
