RRC ID 72178
Author Yada Y, Suga M, Shibukawa R, Sagara Y, Okanishi Y, Enami T, Tsukita K, Kondo T, Imamura K, Sugihara G, Murai T, Inoue H.
Title Establishment of induced pluripotent stem cells from schizophrenia discordant fraternal twins.
Journal Stem Cell Res
Abstract Schizophrenia (SCZ) is one of the major psychiatric disorders. The genetic factor is certainly influential in the onset of the disease but is not decisive. There is no identified molecular/cellular marker of the disease, and the pathomechanism is still unknown. In this study, we generated human induced pluripotent stem cells (iPSCs) derived from SCZ-discordant fraternal twins, and they could contribute to elucidation of the pathomechanism of SCZ.
Volume 55
Pages 102504
Published 2021-8-1
DOI 10.1016/j.scr.2021.102504
PII S1873-5061(21)00351-2
PMID 34419750
MeSH Humans Induced Pluripotent Stem Cells* Schizophrenia* / genetics Twins, Dizygotic
IF 4.495
Resource
Human and Animal Cells Vero(RCB0001)