Reference - Detail
RRC ID | 72178 |
---|---|
Author | Yada Y, Suga M, Shibukawa R, Sagara Y, Okanishi Y, Enami T, Tsukita K, Kondo T, Imamura K, Sugihara G, Murai T, Inoue H. |
Title | Establishment of induced pluripotent stem cells from schizophrenia discordant fraternal twins. |
Journal | Stem Cell Res |
Abstract |
Schizophrenia (SCZ) is one of the major psychiatric disorders. The genetic factor is certainly influential in the onset of the disease but is not decisive. There is no identified molecular/cellular marker of the disease, and the pathomechanism is still unknown. In this study, we generated human induced pluripotent stem cells (iPSCs) derived from SCZ-discordant fraternal twins, and they could contribute to elucidation of the pathomechanism of SCZ. |
Volume | 55 |
Pages | 102504 |
Published | 2021-8-1 |
DOI | 10.1016/j.scr.2021.102504 |
PII | S1873-5061(21)00351-2 |
PMID | 34419750 |
MeSH | Humans Induced Pluripotent Stem Cells* Schizophrenia* / genetics Twins, Dizygotic |
IF | 4.495 |
Resource | |
Human and Animal Cells | Vero(RCB0001) |