Reference - Detail
| RRC ID | 72383 |
|---|---|
| Author | Hamada T, Ui-Tei K, Imaki J, Miyata Y. |
| Title | Molecular cloning of SCDGF-B, a novel growth factor homologous to SCDGF/PDGF-C/fallotein. |
| Journal | Biochem Biophys Res Commun |
| Abstract |
Spinal cord-derived growth factor (SCDGF)/platelet-derived growth factor (PDGF)-C/fallotein has a unique two-domain structure, as it contains two regions homologousto CUB and PDGF/vascular endothelial growth factor (VEGF) domains. In this study, we isolateda novel gene homologous to SCDGF/PDGF-C/fallotein, and named SCDGF-B. The culture supernatant of CHO-K1 cells stably transfected with SCDGF-B showed mitogenic activity as SCDGF/PDGF-C/fallotein did. Although SCDGF-B and SCDGF/PDGF-C/fallotein might be the members of the PDGF/VEGF superfamily of growth factors, they were categorized into a new subfamily in addition to PDGF and VEGF subfamilies. |
| Volume | 280(3) |
| Pages | 733-7 |
| Published | 2001-1-26 |
| DOI | 10.1006/bbrc.2000.4187 |
| PII | S0006-291X(00)94187-1 |
| PMID | 11162582 |
| MeSH | Amino Acid Sequence Animals Base Sequence CHO Cells Cloning, Molecular Cricetinae DNA Primers / genetics Humans Lymphokines / chemistry Lymphokines / genetics* Lymphokines / pharmacology Mitogens / pharmacology Molecular Sequence Data Phylogeny Platelet-Derived Growth Factor / chemistry Platelet-Derived Growth Factor / genetics* Platelet-Derived Growth Factor / pharmacology Protein Structure, Tertiary Rats Recombinant Proteins / chemistry Recombinant Proteins / genetics Recombinant Proteins / pharmacology Sequence Homology, Amino Acid Transfection |
| IF | 2.985 |
| Altmetric score |
オルトメトリクス指標項目
|
| The most frequently cited source | Patent(IFI CLAIMS) |
| Total number of mentions | 8 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Human and Animal Cells | CHO-K1(RCB0285) 10T1/2 (RCB0247) |