RRC ID 72568
著者 Shi D, Zhu C, Lu R, Mao S, Qi Y.
タイトル Intermediate frequency magnetic field generated by a wireless power transmission device does not cause genotoxicity in vitro.
ジャーナル Bioelectromagnetics
Abstract The aim of this study was to evaluate effects of intermediate frequency magnetic fields (IFMF) generated by a wireless power transmission (WPT) based on magnetic resonance from the perspective of cellular genotoxicity on cultured human lens epithelial cells (HLECs). We evaluated the effects of exposure to 90 kHz magnetic fields at 93.36 µT on cellular genotoxicity in vitro for 2 and 4 h. The magnetic flux density is approximately 3.5 times higher than the reference level recommended by the International Commission on Non-Ionizing Radiation Protection (ICNIRP) guidelines. For assessment of genotoxicity, we studied cellular proliferation, apoptosis and DNA damage by Cell Counting Kit-8 (CCK-8) assay, flow cytometry analysis, alkaline comet assay and phosphorylated histone H2AX (γH2AX) foci formation test. We did not detect any effect of a 90 kHz IFMF generated by WPT based on magnetic resonance on cell proliferation, apoptosis, comet assay, and γH2AX foci formation test. Our results indicated that exposure to 90 kHz IFMF generated by WPT based on magnetic resonance at 93.36 µT for 2 and 4 h does not cause detectable cellular genotoxicity.
巻・号 35(7)
ページ 512-8
公開日 2014-10-1
DOI 10.1002/bem.21872
PMID 25196478
MeSH Apoptosis / radiation effects Cell Line Cell Proliferation / radiation effects Comet Assay DNA Damage / radiation effects Epithelium / radiation effects* Flow Cytometry Histones / genetics Histones / radiation effects Humans Lens, Crystalline / radiation effects* Magnetic Fields* Microscopy, Fluorescence Mutagenicity Tests Phosphorylation / drug effects Wireless Technology*
IF 2.278
リソース情報
ヒト・動物細胞 SRA 01/04(RCB1591)