| RRC ID |
72571
|
| 著者 |
Tanaka R, Kikuchi T, Nakasuji S, Ue Y, Shuto D, Igarashi K, Okada R, Yamada T.
|
| タイトル |
A novel 3α-p-Nitrobenzoylmultiflora-7:9(11)-diene-29-benzoate and two new triterpenoids from the seeds of zucchini (Cucurbita pepo L).
|
| ジャーナル |
Molecules
|
| Abstract |
Three novel multiflorane-type triterpenoids, 3α-p-nitrobenzoylmultiflora-7:9(11)-diene-29-benzoate (1), 3α-acetoxymultiflora-7:9(11)-diene-29-benzoate (2), and 3α-acetoxymultiflora-5(6):7:9(11)-triene-29-benzoate (3), along with two known related compounds 4 and 5 were isolated from the seeds of zucchini (Cucurbita pepo L). Their structures were determined on the basis of 1D and 2D NMR spectroscopy and HREIMS. Triterpenoids possessing a nitro group were not isolated previously.
|
| 巻・号 |
18(7)
|
| ページ |
7448-59
|
| 公開日 |
2013-6-26
|
| DOI |
10.3390/molecules18077448
|
| PII |
molecules18077448
|
| PMID |
23803716
|
| PMC |
PMC6269766
|
| MeSH |
Animals
Cell Line, Tumor
Cell Proliferation / drug effects
Cucurbita / cytology
Cucurbita / metabolism*
Drug Discovery
Drug Screening Assays, Antitumor
HL-60 Cells
Humans
Leukemia P388
Melanoma, Experimental / drug therapy
Mice
Neoplasms / drug therapy*
Plant Extracts
Seeds / chemistry*
Seeds / cytology
Triterpenes / chemistry
Triterpenes / isolation & purification
Triterpenes / pharmacology*
|
| IF |
3.267
|
| リソース情報 |
| ヒト・動物細胞 |
B16 melanoma 4A5(RCB0557) |
