| RRC ID |
72808
|
| 著者 |
Kawabata S, Asano K, Miyazawa A, Satoh T, Tabata Y.
|
| タイトル |
Electrodeposition of pronectin for titanium to augment gingival epithelium adhesion.
|
| ジャーナル |
J Tissue Eng Regen Med
|
| Abstract |
This paper is one trial of surface modification of titanium with pronectin F+ (PN) of an artificial protein to enhance gingival adhesion. Titanium plates were electrodeposited in the PN solution to prepare PN-electrodeposited titanium plates. When PN detachment from the PN-electrodeposited titanium plates was investigated, no detachment was observed, in contrast to the case of titanium plates simply coated with PN. A cell culture experiment demonstrated that electrodeposited PN had an inherent ability to enhance the initial attachment of gingival epithelial cells. The PN-electrodeposited titanium plates were implanted between the gingival epithelium and the underlying bone tissue of rabbits to evaluate epithelial growth on the plates and their gingival adhesion. Non-treated and PN-coated titanium plates were used as controls. PN electrodeposition enhanced epithelial growth and adhesion of titanium plates to a significantly great extent compared with PN-coated plates. These findings demonstrate that PN electrodeposition is a promising method to enhance epithelium adhesion onto a titanium surface.
|
| 巻・号 |
7(5)
|
| ページ |
348-52
|
| 公開日 |
2013-5-1
|
| DOI |
10.1002/term.527
|
| PMID |
22294437
|
| MeSH |
Adsorption
Animals
Cell Adhesion / drug effects
Electroplating / methods*
Epithelial Cells / drug effects
Epithelial Cells / pathology
Epithelium / drug effects
Epithelium / pathology*
Fibronectins / pharmacology*
Gingiva / pathology*
Rabbits
Recombinant Proteins / pharmacology
Time Factors
Titanium / pharmacology*
|
| IF |
3.078
|
| リソース情報 |
| ヒト・動物細胞 |
GE1(RCB1709) |
