Reference - Detail
| RRC ID | 72891 |
|---|---|
| Author | Ali AM, Mackeen MM, Hamid M, Aun QB, Zauyah Y, Azimahtol HL, Kawazu K. |
| Title | Cytotoxicity and electron microscopy of cell death induced by goniothalamin. |
| Journal | Planta Med |
| Abstract |
The cytotoxicity of goniothalamin was found to be strong towards both cancerous (HGC-27, MCF-7, PANC-1, HeLa), and non-cancerous (3T3) cell lines, especially in cases of dividing cells. Drug exposure studies indicated that the cytotoxic action of goniothalamin was time- and dose-dependent. At the ultrastructural level, goniothalamin-induced cytotoxicity revealed a necrotic mode of cell death towards MCF-7 cells. |
| Volume | 63(1) |
| Pages | 81-3 |
| Published | 1997-2-1 |
| DOI | 10.1055/s-2006-957611 |
| PMID | 9063100 |
| MeSH | 3T3 Cells Animals Antineoplastic Agents, Phytogenic / pharmacology* Cell Death / drug effects* Humans Mice Microscopy, Electron Pyrones / pharmacology* Tumor Cells, Cultured |
| IF | 2.687 |
| Altmetric score |
オルトメトリクス指標項目
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| Total number of mentions | 0 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Human and Animal Cells | HGC-27(RCB0500) |