Reference - Detail
| RRC ID | 72892 |
|---|---|
| Author | Oh KW, Kim HS, Wagner GC. |
| Title | Ginseng total saponin inhibits the dopaminergic depletions induced by methamphetamine. |
| Journal | Planta Med |
| Abstract |
Pretreatment with ginseng total saponin (GTS) reduced the magnitude of the methamphetamine-induced dopamine (DA), 3,4-dihydroxyphenylacetic acid (DOPAC), and homovanillinic acid (HVA) depletions. It is suggested that GTS can, in part, prevent the methamphetamine-induced striatal dopaminergic depletions. |
| Volume | 63(1) |
| Pages | 80-1 |
| Published | 1997-2-1 |
| DOI | 10.1055/s-2006-957610 |
| PMID | 9063099 |
| MeSH | 3,4-Dihydroxyphenylacetic Acid / metabolism Animals Chromatography, High Pressure Liquid Corpus Striatum / metabolism Dopamine / metabolism Dopamine Uptake Inhibitors / antagonists & inhibitors* Electrochemistry Homovanillic Acid / metabolism Injections, Intraperitoneal Male Methamphetamine / antagonists & inhibitors* Mice Panax / chemistry* Plants, Medicinal* Saponins / administration & dosage Saponins / pharmacology* |
| IF | 2.687 |
| Resource | |
| Human and Animal Cells | HGC-27(RCB0500) 3T3, mouse fibroblast |