RRC ID 72962
Author Mu Q, Cui K, Wang ZJ, Matsuda T, Cui W, Kato H, Namiki S, Yamazaki T, Frauenlob M, Nonoyama T, Tsuda M, Tanaka S, Nakajima T, Gong JP.
Title Force-triggered rapid microstructure growth on hydrogel surface for on-demand functions.
Journal Nat Commun
Abstract Living organisms share the ability to grow various microstructures on their surface to achieve functions. Here we present a force stamp method to grow microstructures on the surface of hydrogels based on a force-triggered polymerisation mechanism of double-network hydrogels. This method allows fast spatial modulation of the morphology and chemistry of the hydrogel surface within seconds for on-demand functions. We demonstrate the oriented growth of cells and directional transportation of water droplets on the engineered hydrogel surfaces. This force-triggered method to chemically engineer the hydrogel surfaces provides a new tool in addition to the conventional methods using light or heat, and will promote the wide application of hydrogels in various fields.
Volume 13(1)
Pages 6213
Published 2022-10-20
DOI 10.1038/s41467-022-34044-8
PII 10.1038/s41467-022-34044-8
PMID 36266283
PMC PMC9585076
MeSH Hydrogels* / chemistry Water* / chemistry
IF 12.121
Resource
Human and Animal Cells C2C12(RCB0987)