| RRC ID |
73541
|
| Author |
Ecke F, Han BA, Hörnfeldt B, Khalil H, Magnusson M, Singh NJ, Ostfeld RS.
|
| Title |
Population fluctuations and synanthropy explain transmission risk in rodent-borne zoonoses.
|
| Journal |
Nat Commun
|
| Abstract |
Population fluctuations are widespread across the animal kingdom, especially in the order Rodentia, which includes many globally important reservoir species for zoonotic pathogens. The implications of these fluctuations for zoonotic spillover remain poorly understood. Here, we report a global empirical analysis of data describing the linkages between habitat use, population fluctuations and zoonotic reservoir status in rodents. Our quantitative synthesis is based on data collated from papers and databases. We show that the magnitude of population fluctuations combined with species' synanthropy and degree of human exploitation together distinguish most rodent reservoirs at a global scale, a result that was consistent across all pathogen types and pathogen transmission modes. Our spatial analyses identified hotspots of high transmission risk, including regions where reservoir species dominate the rodent community. Beyond rodents, these generalities inform our understanding of how natural and anthropogenic factors interact to increase the risk of zoonotic spillover in a rapidly changing world.
|
| Volume |
13(1)
|
| Pages |
7532
|
| Published |
2022-12-7
|
| DOI |
10.1038/s41467-022-35273-7
|
| PII |
10.1038/s41467-022-35273-7
|
| PMID |
36477188
|
| PMC |
PMC9729607
|
| MeSH |
Animals
Humans
Rodentia*
|
| IF |
12.121
|
| Resource |
| GBIF |
Long-term fauna and flora records of the experimental forests of the Forest Research Station of Hokkaido University, Japan
Mammal specimens of Okinawa Prefectural Museum & Art Museum
Mammal specimens of Oiso Municipal Museum
Mammal specimens of Ryukyu University Museum (Fujukan)
Mammalians Specimens of Akita Prefectural Museum
Ibaraki Nature Museum, Mammals collection
Mammal collection of National Museum of Nature and Science
Mammals specimens of Taga Town Museum, Shiga Pref., Japan
Mammal specimens of Kawasaki Municipal Science Museum
Mammal specimen database of Kanagawa Prefectural Museum of Natural History
Gunma Museum of Natural History, Mammal Specimen
Mammal specimens of Takatsuki Nature Museum (Aquapia Akutagawa)
Mammal specimens of Saitama Museum of Natural History |
