| RRC ID |
73832
|
| Author |
Junker K, Bravo Ruiz G, Lorenz A, Walker L, Gow NAR, Wendland J.
|
| Title |
The mycoparasitic yeast Saccharomycopsis schoenii predates and kills multi-drug resistant Candida auris.
|
| Journal |
Sci Rep
|
| Abstract |
Candida auris has recently emerged as a multi-drug resistant fungal pathogen that poses a serious global health threat, especially for patients in hospital intensive care units (ICUs). C. auris can colonize human skin and can spread by physical contact or contaminated surfaces and equipment. Here, we show that the mycoparasitic yeast Saccharomycopsis schoenii efficiently kills both sensitive and multi-drug resistant isolates of C. auris belonging to the same clade, as well as clinical isolates of other pathogenic species of the Candida genus suggesting novel approaches for biocontrol.
|
| Volume |
8(1)
|
| Pages |
14959
|
| Published |
2018-10-8
|
| DOI |
10.1038/s41598-018-33199-z
|
| PII |
10.1038/s41598-018-33199-z
|
| PMID |
30297756
|
| PMC |
PMC6175896
|
| MeSH |
Antibiosis*
Antifungal Agents / pharmacology
Candida / cytology
Candida / drug effects
Candida / physiology*
Candidiasis / drug therapy
Candidiasis / microbiology*
Drug Resistance, Multiple, Fungal
Humans
Saccharomycopsis / cytology
Saccharomycopsis / physiology*
|
| IF |
3.998
|
| Resource |
| Yeast |
FY15112 |
