| RRC ID |
74028
|
| 著者 |
Lee SA, Kim M, Esterhuizen M, Le VV, Kang M, Ko SR, Oh HM, Kim YJ, Ahn CY.
|
| タイトル |
An acceleration of carotenoid production and growth of Haematococcus lacustris induced by host-microbiota network interaction.
|
| ジャーナル |
Microbiol Res
|
| Abstract |
Haematococcus lacustris is a chlamydomonadalean with high biotechnological interest owing to its capacity to produce astaxanthin, a valuable secondary carotenoid with extraordinary antioxidation properties. However, its prolonged growth has limited its utility commercially. Thus, rapid growth to attain high densities of H. lacustris cells optimally producing astaxanthin is an essential biotechnological target to facilitate profitable commercialisation. Our study focused on characterising the bacterial communities associated with the alga's phycosphere by metagenomics. Subsequently, we altered the bacterial consortia in combined co-culture with key beneficial bacteria to optimise the growth of H. lacustris. The algal biomass increased by up to 2.1-fold in co-cultures, leading to a 1.6-fold increase in the astaxanthin yield. This study attempted to significantly improve the H. lacustris growth rate and biomass yield via Next-Generation Sequencing analysis and phycosphere bacterial augmentation, highlighting the possibility to overcome the hurdles associated with astaxanthin production by H. lacustris at a commercial scale.
|
| 巻・号 |
262
|
| ページ |
127097
|
| 公開日 |
2022-9-1
|
| DOI |
10.1016/j.micres.2022.127097
|
| PII |
S0944-5013(22)00137-9
|
| PMID |
35751943
|
| MeSH |
Acceleration
Bacteria / genetics
Biomass
Carotenoids
Chlorophyta*
Microbiota*
|
| IF |
3.97
|
| リソース情報 |
| 藻類 |
NIES-144 |
