Reference - Detail
| RRC ID | 74111 |
|---|---|
| Author | Katsuma S, Hirota K, Matsuda-Imai N, Fukui T, Muro T, Nishino K, Kosako H, Shoji K, Takanashi H, Fujii T, Arimura SI, Kiuchi T. |
| Title | A Wolbachia factor for male killing in lepidopteran insects. |
| Journal | Nat Commun |
| Abstract |
Bacterial symbionts, such as Wolbachia species, can manipulate the sexual development and reproduction of their insect hosts. For example, Wolbachia infection induces male-specific death in the Asian corn borer Ostrinia furnacalis by targeting the host factor Masculinizer (Masc), an essential protein for masculinization and dosage compensation in lepidopteran insects. Here we identify a Wolbachia protein, designated Oscar, which interacts with Masc via its ankyrin repeats. Embryonic expression of Oscar inhibits Masc-induced masculinization and leads to male killing in two lepidopteran insects, O. furnacalis and the silkworm Bombyx mori. Our study identifies a mechanism by which Wolbachia induce male killing of host progeny. |
| Volume | 13(1) |
| Pages | 6764 |
| Published | 2022-11-14 |
| DOI | 10.1038/s41467-022-34488-y |
| PII | 10.1038/s41467-022-34488-y |
| PMID | 36376299 |
| PMC | PMC9663696 |
| MeSH | Animals Bombyx* / genetics Bombyx* / metabolism Dosage Compensation, Genetic Insect Proteins / genetics Insect Proteins / metabolism Male Moths* / microbiology Wolbachia* / metabolism |
| IF | 12.121 |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | X(Twitter) |
| Total number of mentions | 41 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Silkworms | p50 |