論文 - 詳細
| RRC ID | 74282 |
|---|---|
| 著者 | Watanabe C, Kimizuka Y, Fujikura Y, Hamamoto T, Watanabe A, Yaguchi T, Sano T, Suematsu R, Kato Y, Miyata J, Matsukuma S, Kawana A. |
| タイトル | Mixed Infection of Cytomegalovirus and Pulmonary Nocardiosis Caused by Nocardia elegans Diagnosed Using Nanopore Sequencing Technology. |
| ジャーナル | Intern Med |
| Abstract |
A 69-year-old woman who had undergone renal transplantation and was receiving sulfamethoxazole/trimethoprim (ST) developed pulmonary nocardiosis. To our knowledge, this is the first report of the identification of Nocardia elegans using nanopore sequencing, supported by 16S rDNA capillary sequencing findings. Chest computed tomography performed after ST initiation revealed significant improvement of the pulmonary shadows compared to previous findings. We herein report the value of nanopore sequencing for rapid identification of rare pathogens, such as Nocardia elegans. Furthermore, our findings suggest that Nocardia may infect even patients receiving ST, which is currently the most effective prophylactic drug. |
| 巻・号 | 61(10) |
| ページ | 1613-1617 |
| 公開日 | 2022-5-15 |
| DOI | 10.2169/internalmedicine.7639-21 |
| PMID | 34707041 |
| PMC | PMC9177376 |
| MeSH | Aged Coinfection* / complications Cytomegalovirus Female Humans Nanopore Sequencing* Nocardia* / genetics Nocardia Infections* / diagnosis Technology Trimethoprim, Sulfamethoxazole Drug Combination / therapeutic use |
| IF | 1.005 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
|
| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 3 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 病原真核微生物 | Nocardia elegans IFM 12178 |