論文 - 詳細
| RRC ID | 74416 |
|---|---|
| 著者 | Liu J, Liu ZX, Li JJ, Zeng ZL, Wang JH, Luo XJ, Wong CW, Zheng JB, Pu HY, Mo HY, Sheng H, Wu QN, Li H, Wan G, Li B, Wang DS, Xu RH, Ju HQ. |
| タイトル | The Macrophage-Associated LncRNA MALR Facilitates ILF3 Liquid-Liquid Phase Separation to Promote HIF1α Signaling in Esophageal Cancer. |
| ジャーナル | Cancer Res |
| Abstract |
Secretion of TNFα by tumor-associated macrophages stimulates cancer cells to upregulate lncRNA MALR, which induces ILF3 liquid-liquid phase separation and activation of HIF1α signaling to promote cancer progression. |
| 巻・号 | 83(9) |
| ページ | 1476-1489 |
| 公開日 | 2023-5-2 |
| DOI | 10.1158/0008-5472.CAN-22-1922 |
| PII | 709866 |
| PMID | 36264156 |
| MeSH | Cell Line, Tumor Cell Proliferation Esophageal Neoplasms* / genetics Esophageal Squamous Cell Carcinoma* / genetics Gene Expression Regulation, Neoplastic Humans Macrophages Nuclear Factor 90 Proteins / genetics RNA, Long Noncoding* / genetics |
| IF | 9.727 |
| リソース情報 | |
| ヒト・動物細胞 | TE-9(RCB1988) TE-11(RCB2100) |