| RRC ID |
74638
|
| 著者 |
Suito T, Nagao K, Juni N, Hara Y, Sokabe T, Atomi H, Umeda M.
|
| タイトル |
Regulation of thermoregulatory behavior by commensal bacteria in Drosophila.
|
| ジャーナル |
Biosci Biotechnol Biochem
|
| Abstract |
Commensal bacteria affect many aspects of host physiology. In this study, we focused on the role of commensal bacteria in the thermoregulatory behavior of Drosophila melanogaster. We demonstrated that the elimination of commensal bacteria caused an increase in the preferred temperature of Drosophila third-instar larvae without affecting the activity of transient receptor potential ankyrin 1 (TRPA1)-expressing thermosensitive neurons. We isolated eight bacterial strains from the gut and culture medium of conventionally reared larvae and found that the preferred temperature of the larvae was decreased by mono-association with Lactobacillus plantarum or Corynebacterium nuruki. Mono-association with these bacteria did not affect the indices of energy metabolism such as ATP and glucose levels of larvae, which are closely linked to thermoregulation in animals. Thus, we show a novel role for commensal bacteria in host thermoregulation and identify two bacterial species that affect thermoregulatory behavior in Drosophila.
|
| 巻・号 |
86(8)
|
| ページ |
1060-1070
|
| 公開日 |
2022-7-22
|
| DOI |
10.1093/bbb/zbac087
|
| PII |
6603831
|
| PMID |
35671161
|
| MeSH |
Animals
Bacteria
Body Temperature Regulation
Drosophila*
Drosophila melanogaster* / microbiology
Drosophila melanogaster* / physiology
Larva / physiology
Symbiosis
|
| IF |
1.516
|
| リソース情報 |
| ショウジョウバエ |
DGRC#108749 |
