RRC ID 74879
Author Sato S, Sofian FF, Paulin DA, Kobayashi S, Koseki T, Shiono Y.
Title Integracide derivatives produced by endophyte Fusarium armeniacum M-3 isolated from Digitaria ciliaris.
Journal Nat Prod Res
Abstract Two new integracides, dedimethyl integracide B (1) and integracide K (2), were isolated from rice cultures of Fusarium armeniacum M-3, an endophyte isolated from Digitaria ciliaris, together with the known terpenoids, integracide B (3) and 2-deoxy-integracide B (4). Assignment of the signals in the 1H and 13C NMR spectra of 1 and 2 was achieved using DEPT, HMQC, HMBC, and NOESY spectra. Compound 2 exhibited moderate cytotoxicity against HeLa cells.
Pages 1-8
Published 2023-1-11
DOI 10.1080/14786419.2022.2164580
PMID 36628994
MeSH Endophytes* / chemistry Fusarium* / chemistry Fusarium* / drug effects HeLa Cells Humans Magnetic Resonance Spectroscopy Molecular Structure Oryza / microbiology Terpenes / chemistry Terpenes / isolation & purification Terpenes / pharmacology
IF 2.158
Resource
Human and Animal Cells HeLa