Reference - Detail
| RRC ID | 75228 |
|---|---|
| Author | Liu X, Wang D, Wang S, Fan W, Yang Y, Gao P, Chen M, Yang W, Cai K. |
| Title | Promoting osseointegration by in situ biosynthesis of metal ion-loaded bacterial cellulose coating on titanium surface. |
| Journal | Carbohydr Polym |
| Abstract |
The biologically inert and excessive elastic modulus of Ti implant surface, as well as the excessive gap between implant and host, will lead to poor bone integration even implant failure. To solve the above problems, in this study, a method for functional Ti implant is reported, in which metal ions-containing bacterial cellulose (BC) coating is introduced in situ on the surface of Ti with complex shapes. Magnesium and strontium ions can be loaded into BC by in situ biosynthesis, which have great effects on the growth of bacteria and the structure of cellulose. In addition, both in vitro and in vivo experiments confirmed that the in situ preparation of functional BC coating on the Ti surface can integrate the operative crevices and promote osteogenesis. This simple and novel method for functional Ti implants has potential application value in clinical bone tissue repair and regeneration. |
| Volume | 297 |
| Pages | 120022 |
| Published | 2022-12-1 |
| DOI | 10.1016/j.carbpol.2022.120022 |
| PII | S0144-8617(22)00927-4 |
| PMID | 36184141 |
| MeSH | Bacteria Cellulose Ions Magnesium Osseointegration* Osteogenesis Strontium / chemistry Surface Properties Titanium* / chemistry Titanium* / pharmacology |
| Altmetric score |
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| The most frequently cited source | Patent(IFI CLAIMS) |
| Total number of mentions | 2 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| General Microbes | JCM 9730 |