Reference - Detail
| RRC ID | 76390 |
|---|---|
| Author | Suzuki F, Miyamoto S, Takita M, Oshita M, Watanabe Y, Kakizuka A, Narumiya S, Taniguchi T, Muramatsu I. |
| Title | Cloning, functional expression and tissue distribution of rabbit alpha 1d-adrenoceptor. |
| Journal | Biochim Biophys Acta |
| Abstract |
We have cloned a cDNA encoding rabbit alpha 1d-adrenoceptor from the rabbit liver cDNA library. The deduced amino-acid sequence of this clone encodes a protein of 576 amino acids that shows strong sequence homology to previously cloned human, rat and mouse alpha 1d-adrenoceptors. The pharmacological radioligand binding properties of this clone expressed in COS-7 cells were similar to those of rat alpha 1d-adrenoceptors. Competitive RT/PCR assays revealed wide tissue distribution of the alpha 1d-adrenoceptor mRNA in rabbit, especially abundant in vas deferens, aorta, prostate and cerebral cortex. |
| Volume | 1323(1) |
| Pages | 6-11 |
| Published | 1997-1-14 |
| DOI | 10.1016/s0005-2736(96)00229-5 |
| PII | S0005-2736(96)00229-5 |
| PMID | 9030207 |
| MeSH | Amino Acid Sequence Animals Base Sequence COS Cells Cloning, Molecular DNA Primers / genetics DNA, Complementary / genetics Gene Expression Humans Male Mice Molecular Sequence Data Polymerase Chain Reaction RNA, Messenger / genetics RNA, Messenger / metabolism Rabbits Rats Receptors, Adrenergic, alpha-1 / genetics* Receptors, Adrenergic, alpha-1 / metabolism* Sequence Homology, Amino Acid Tissue Distribution |
| IF | 3.411 |
| Altmetric score |
オルトメトリクス指標項目
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| Total number of mentions | 0 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Human and Animal Cells | COS-7(RCB0539) |