RRC ID |
76391
|
Author |
Ida C, Ogata S.
|
Title |
Changes in NAD content induced by nicotinic acid-related compounds in K562 cells during differentiation.
|
Journal |
Biosci Biotechnol Biochem
|
Abstract |
Two nicotinic acid-related compounds were found to induce erythroid differentiation in K562 cells. We investigated the changes in nicotinamide adenine dinucleotide (NAD) content induced by nicotinic acid-related compounds during differentiation. The NAD content was reduced by a treatment with nicotinic acid and isonicotinic acid. These results provide important clues toward elucidating the erythroid differentiation mechanism.
|
Volume |
77(7)
|
Pages |
1583-5
|
Published |
2013-1-1
|
DOI |
10.1271/bbb.130131
|
PII |
DN/JST.JSTAGE/bbb/130131
|
PMID |
23832340
|
MeSH |
Cell Differentiation / drug effects*
Humans
K562 Cells
NAD / metabolism*
Niacin / pharmacology*
Time Factors
|
IF |
1.516
|
Resource |
Human and Animal Cells |
K562 |