RRC ID 76391
Author Ida C, Ogata S.
Title Changes in NAD content induced by nicotinic acid-related compounds in K562 cells during differentiation.
Journal Biosci Biotechnol Biochem
Abstract Two nicotinic acid-related compounds were found to induce erythroid differentiation in K562 cells. We investigated the changes in nicotinamide adenine dinucleotide (NAD) content induced by nicotinic acid-related compounds during differentiation. The NAD content was reduced by a treatment with nicotinic acid and isonicotinic acid. These results provide important clues toward elucidating the erythroid differentiation mechanism.
Volume 77(7)
Pages 1583-5
Published 2013-1-1
DOI 10.1271/bbb.130131
PII DN/JST.JSTAGE/bbb/130131
PMID 23832340
MeSH Cell Differentiation / drug effects* Humans K562 Cells NAD / metabolism* Niacin / pharmacology* Time Factors
IF 1.516
Resource
Human and Animal Cells K562