論文 - 詳細
| RRC ID | 76415 |
|---|---|
| 著者 | Tsuji M, Taira H, Udagawa T, Aoki T, Hirayama T, Nagasawa H. |
| タイトル | Synthesis and photochemical properties of caged peroxides for photocontrol of cellular oxidative stress. |
| ジャーナル | Chem Commun (Camb) |
| Abstract |
We developed a caged hydroperoxide, BhcTBHP, releasing prooxidant TBHP under blue light irradiation. MitoTBHP with triphenylphosphonium at position 7 triggered selective oxidative stress and membrane depolarization in mitochondria upon photoirradiation. This study presents a powerful tool for studying redox signaling and oxidative stress in living cells. |
| 巻・号 | 59(44) |
| ページ | 6706-6709 |
| 公開日 | 2023-5-30 |
| DOI | 10.1039/d3cc01192e |
| PMID | 37190960 |
| MeSH | Hydrogen Peroxide Oxidation-Reduction Oxidative Stress* Peroxides* / pharmacology Reactive Oxygen Species tert-Butylhydroperoxide / pharmacology |
| IF | 5.996 |
| リソース情報 | |
| ヒト・動物細胞 | MCF7(RCB1904) |