| RRC ID |
77429
|
| 著者 |
Elif Didem Örs, Şenay Burçin Alkan, Abdullah Öksüz
|
| タイトル |
Possible Effect of Astaxanthin on Obesity-related Increased COVID-19
Infection Morbidity and Mortality
|
| ジャーナル |
Current Nutrition & Food Science
|
| Abstract |
Abstract:
Obesity is defined by the World Health Organisation (WHO) as a body mass index
equal to 30 kg/m2 or greater. It is an important and escalating global public health problem.
Obesity is known to cause low-grade chronic inflammation, increasing the burden of noncommunicable
and possibly communicable diseases. There is considerable evidence that obesity is
associated with an increased risk of contracting coronavirus disease 2019 (COVID-19) infection
as well as significantly higher COVID-19 morbidity and mortality. It appears plausible
that controlling the chronic systemic low-grade inflammation associated with obesity may have
a positive impact on the symptoms and the prognosis of COVID-19 disease in obese patients.
Astaxanthin (ASTX) is a naturally occurring carotenoid with anti-inflammatory, antioxidant,
and immunomodulatory activities. As a nutraceutical agent, it is used as a preventative and a
co-treatment in a number of systemic neurological, cardiovascular, and metabolic diseases.
This review article will discuss the pathogenesis of COVID-19 infection and the effect of
ASTX on obesity and obesity-related inflammation. The potential positive impact of ASTX anti-
inflammatory properties in obese COVID-19 patients will be discussed.
|
| 巻・号 |
18
|
| ページ |
265-273
|
| 公開日 |
2022-3-1
|
| DOI |
10.2174/1573401317666211011105732
|
| リソース情報 |
| 藻類 |
NIES-144 |
