RRC ID 77812
Author Satake H, Sasakura Y.
Title The neuroendocrine system of Ciona intestinalis Type A, a deuterostome invertebrate and the closest relative of vertebrates.
Journal Mol Cell Endocrinol
Abstract Deuterostome invertebrates, including echinoderms, hemichordates, cephalochordates, and urochordates, exhibit common and species-specific morphological, developmental, physiological, and behavioral characteristics that are regulated by neuroendocrine and nervous systems. Over the past 15 years, omics, genetic, and/or physiological studies on deuterostome invertebrates have identified low-molecular-weight transmitters, neuropeptides and their cognate receptors, and have clarified their various biological functions. In particular, there has been increasing interest on the neuroendocrine and nervous systems of Ciona intestinalis Type A, which belongs to the subphylum Urochordata and occupies the critical phylogenetic position as the closest relative of vertebrates. During the developmental stage, gamma-aminobutylic acid, D-serine, and gonadotropin-releasing hormones regulate metamorphosis of Ciona. In adults, the neuropeptidergic mechanisms underlying ovarian follicle growth, oocyte maturation, and ovulation have been elucidated. This review article provides the most recent and fundamental knowledge of the neuroendocrine and nervous systems of Ciona, and their evolutionary aspects.
Volume 582
Pages 112122
Published 2023-12-16
DOI 10.1016/j.mce.2023.112122
PII S0303-7207(23)00273-3
PMID 38109989
MeSH Animals Ciona intestinalis* / genetics Female Invertebrates Neurosecretory Systems Phylogeny Vertebrates / genetics
IF 3.871
Resource
C.intestinalis / (O.japonicus) Wild C. int Tg[MiCiVGLUT4.3K]2 Tg[MiCignrh1K]2 Tg[MiCiTHK]2 Tg[MiCiVACHTC]2