Reference - Detail
RRC ID | 78572 |
---|---|
Author | I. Bányász, I. Rajta, V. Havránek, A. Mackova, A. J. Laki, M. S. Z. Kellermayer, Z. Szittner, S. Kurunczi, Sz. Novák, I. Székács, R. Horváth, M. Fried, G. U. L. Nagy |
Title | Design, fabrication, and characterization of picowell arrays on cyclic olefin copolymer surfaces generated with a 10.5 MeV N4+ ion microbeam |
Journal | Applied Physics Letters |
Abstract |
Handling of picoliter-to-nanoliter-scale volumes and objects has increasing importance in life sciences. This is the volume scale of cell extractions and individual living cells. Here, we introduce a method of generating a picoliter-scale device by direct writing of picowell arrays on a ZEONOR™ copolymer surface with high-energy medium-mass ion microbeam. Arrays of various microstructures were written in the sample using a microbeam of 10.5 MeV N4+ ions at various implanted ion fluences. The best array was obtained by implantation of annuli of 10 and 11 μm of inner and outer diameters with a fluence of 7.8 × 1012 ions/cm2. |
Volume | 123 |
Published | 2023-7-31 |
DOI | 10.1063/5.0155681 |
Resource | |
Human and Animal Cells | HeLa/Fucci(RCB2812) |