| RRC ID |
79447
|
| 著者 |
Nakamura S, Fujimoto K, Nakashima S, Matsumoto T, Miura T, Uno K, Matsuda H, Yoshikawa M.
|
| タイトル |
Medicinal flowers. XXXVI.1) Acylated oleanane-type triterpene saponins with inhibitory effects on melanogenesis from the flower buds of Chinese Camellia japonica.
|
| ジャーナル |
Chem Pharm Bull (Tokyo)
|
| Abstract |
Four acylated oleanane-type triterpene oligoglycosides, sanchakasaponins E-H, were isolated from the flower buds of Camellia japonica cultivated in Yunnan province, China, together with four known triterpene oligoglycosides. The chemical structures of the new triterpene oligoglycosides were elucidated on the basis of chemical and physicochemical evidence. The inhibitory effects of the triterpene oligoglycoside constituents on melanogenesis in theophylline-stimulated B16 melanoma 4A5 cells were investigated.
|
| 巻・号 |
60(6)
|
| ページ |
752-8
|
| 公開日 |
2012-1-1
|
| DOI |
10.1248/cpb.60.752
|
| PII |
DN/JST.JSTAGE/cpb/60.752
|
| PMID |
22689427
|
| MeSH |
Acylation
Animals
Antineoplastic Agents / chemistry
Antineoplastic Agents / pharmacology
Camellia / chemistry*
Cell Survival / drug effects
Flowers / chemistry*
Magnetic Resonance Spectroscopy
Medicine, Chinese Traditional
Melanoma, Experimental
Methanol / chemistry
Mice
Molecular Structure
Oleanolic Acid / chemistry*
Oleanolic Acid / pharmacology
Saponins / chemistry*
Saponins / pharmacology
|
| IF |
1.416
|
| リソース情報 |
| ヒト・動物細胞 |
B16 melanoma 4A5(RCB0557) |
