RRC ID 79857
著者 Ozawa K, Mochizuki K, Takagi D, Ishida K, Sunada A, Ohkusu K, Kamei K, Hashimoto A, Tanaka K.
タイトル Identification and antifungal sensitivity of two new species of Diaporthe isolated.
ジャーナル J Infect Chemother
Abstract Diaporhte species are plant pathogens rarely involved in human diseases, especially eye diseases. We report our findings in two undescribed Diaporhte species. Both were identified by their morphological characteristics and by DNA sequence analyses. In Case 1, an 81-year-old male farmer who had pterygium surgery 7 years earlier developed keratitis and the causal fungus was identified as a new species of Diaporthe, D. oculi. This species can be distinguished from the closely related D. limonicola on Citrus limon (Rutaceae) by the ITS, tef1, and TUB (515/520 = 99.0% in ITS, 315/324 = 97.2% in tef1, and 601/614 = 97.9% in TUB). The isolate from Case 2, a 68-year-old man with a rose thorn injury, was also identified as a new Diaporthe species, D. pseudooculi. Phylogenetically, D. pseudooculi is different from the closely related D. podocarpi-macrophylli by the ITS, tef1, and TUB (525/531 = 98.9% in ITS, 314/333 = 94.3% in tef1, and 436/442 = 98.6% in TUB). We report on the identification, drug sensitivity, and treatment outcomes for these two new species of Diaporthe, D. oculi and D. pseudooculi.
巻・号 25(2)
ページ 96-103
公開日 2019-2-1
DOI 10.1016/j.jiac.2018.10.008
PII S1341-321X(18)30409-4
PMID 30424948
MeSH Aged Aged, 80 and over Antifungal Agents* / pharmacology Antifungal Agents* / therapeutic use Ascomycota* / classification Ascomycota* / drug effects Ascomycota* / genetics Ascomycota* / isolation & purification DNA, Fungal / analysis DNA, Fungal / genetics Eye Infections, Fungal* / diagnosis Eye Infections, Fungal* / drug therapy Eye Infections, Fungal* / microbiology Humans Male Microbial Sensitivity Tests Phylogeny
リソース情報
一般微生物 JCM 32617 JCM 32616