論文 - 詳細
| RRC ID | 80607 |
|---|---|
| 著者 | Komano Y, Fukao K, Shimada K, Naito H, Ishihara Y, Fujii T, Kokubo T, Daida H. |
| タイトル | Effects of Ingesting Food Containing Heat-Killed Lactococcus lactis Strain Plasma on Fatigue and Immune-Related Indices after High Training Load: A Randomized, Double-Blind, Placebo-Controlled, and Parallel-Group Study. |
| ジャーナル | Nutrients |
| Abstract |
Lactococcus lactis strain Plasma (LC-Plasma) is a unique lactic acid bacterium that activates plasmacytoid dendritic cells (pDCs). We evaluated the effect of LC-Plasma on fatigue indices and dendritic cells activity in athletes after 14 days' continuous exercise load. Thirty-seven participants were divided into two groups and consumed placebo (PL) or LC-Plasma capsules (containing 100 billion cells) daily for 14 days. Maturation markers on dendritic cells, blood parameters, physiological indices, and fatigue-related indices were recorded on days 1 and 15 (before and after exercise). Cumulative days of symptoms relating to physical conditions were also recorded during the continuous exercise period. We observed that CD86 as a maturation marker on pDCs was significantly higher and that cumulative days of fatigue were significantly fewer in the LC-Plasma group than in the Placebo group on day 15. We also conducted 2 h ergometer exercise on day 15 to evaluate fatigue. The results showed that autonomic fatigue parameters (LF/HF) were significantly lower in the LC-Plasma group. These results suggest that LC-Plasma supplementation alleviates fatigue accumulation and increases pDC activity caused by a continuous high training load. |
| 巻・号 | 15(7) |
| 公開日 | 2023-4-4 |
| DOI | 10.3390/nu15071754 |
| PII | nu15071754 |
| PMID | 37049594 |
| PMC | PMC10096552 |
| MeSH | Dendritic Cells / microbiology Double-Blind Method Exercise Fatigue Hot Temperature Humans Lactococcus lactis* / physiology |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | News |
| 各媒体での言及数の合計 | 8 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 7.0 |
| リソース情報 | |
| 一般微生物 | JCM 5805 |