RRC ID 80988
Author Hamada N, Okawa S, Ishiga M, Yuzurio S, Suwaki T, Yaguchi T, Kimura G, Tanimoto Y.
Title An immunocompetent case of chronic pulmonary aspergillosis caused by Aspergillusviridinutans.
Journal Respir Investig
Abstract We encountered an extremely rare immunocompetent case of chronic pulmonary aspergillosis (CPA) caused by Aspergillus viridinutans. A 74-year-old woman was admitted with fever and hemoptysis. Chest computed tomography revealed a nodule in the left upper lobe. Bronchoscopy was performed, and the transbronchial biopsy specimen revealed Aspergillus fungi. Treatment of the nodule was initially ineffective with voriconazole but effective with liposomal amphotericin B. The causative organism was later identified as A. viridinutans based on the gene sequence of β-tubulin. This is the first immunocompetent case of CPA caused by A. viridinutans.
Volume 62(1)
Pages 164-166
Published 2024-1-1
DOI 10.1016/j.resinv.2023.11.008
PII S2212-5345(23)00112-0
PMID 38141529
MeSH Aged Antifungal Agents Bronchoscopy Female Humans Lung / pathology Pulmonary Aspergillosis* / diagnosis Pulmonary Aspergillosis* / drug therapy Voriconazole / therapeutic use
Pathogenic eukaryotic microorganisms Aspergillus viridinutans IFM 55266