RRC ID 81384
Author Wilson Leung, Nicole Torosin, Weihuan Cao, Laura K Reed, Cindy Arrigo, Sarah C R Elgin, Christopher E Ellison
Title Long-read genome assemblies for the study of chromosome expansion: Drosophila kikkawai, Drosophila takahashii, Drosophila bipectinata, and Drosophila ananassae
Journal G3: Genes, Genomes, Genetics
Abstract Flow cytometry estimates of genome sizes among species of Drosophila show a 3-fold variation, ranging from ∼127 Mb in Drosophila mercatorum to ∼400 Mb in Drosophila cyrtoloma. However, the assembled portion of the Muller F element (orthologous to the fourth chromosome in Drosophila melanogaster) shows a nearly 14-fold variation in size, ranging from ∼1.3 Mb to >18 Mb. Here, we present chromosome-level long-read genome assemblies for 4 Drosophila species with expanded F elements ranging in size from 2.3 to 20.5 Mb. Each Muller element is present as a single scaffold in each assembly. These assemblies will enable new insights into the evolutionary causes and consequences of chromosome size expansion.
Volume 13
Published 2023-9-30
DOI 10.1093/g3journal/jkad191
PMID 37611223
PMC PMC10542312
MeSH Animals Chromosomes / genetics Drosophila* / genetics Drosophila melanogaster* / genetics Genome
Resource
Drosophila E-12201