Reference - Detail
| RRC ID | 81595 |
|---|---|
| Author | Ichikawa K, Horiuchi H. |
| Title | Fate Decisions of Chicken Primordial Germ Cells (PGCs): Development, Integrity, Sex Determination, and Self-Renewal Mechanisms. |
| Journal | Genes (Basel) |
| Abstract |
Primordial germ cells (PGCs) are precursor cells of sperm and eggs. The fate decisions of chicken PGCs in terms of their development, integrity, and sex determination have unique features, thereby providing insights into evolutionary developmental biology. Additionally, fate decisions in the context of a self-renewal mechanism have been applied to establish culture protocols for chicken PGCs, enabling the production of genome-edited chickens and the conservation of genetic resources. Thus, studies on the fate decisions of chicken PGCs have significantly contributed to both academic and industrial development. Furthermore, studies on fate decisions have rapidly advanced owing to the recent development of essential research technologies, such as genome editing and RNA sequencing. Here, we reviewed the status of fate decisions of chicken PGCs and provided insight into other important research issues that require attention. |
| Volume | 14(3) |
| Published | 2023-2-28 |
| DOI | 10.3390/genes14030612 |
| PII | genes14030612 |
| PMID | 36980885 |
| PMC | PMC10048776 |
| MeSH | Animals Chickens* / genetics Gene Editing / methods Germ Cells Male Semen* Spermatozoa |
| IF | 3.759 |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | X(Twitter) |
| Total number of mentions | 2 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Chicken / Quail | |