RRC ID 82399
Author Li F, Xie W, Ding X, Xu K, Fu X.
Title Phytochemical and pharmacological properties of the genus Tamarix: a comprehensive review.
Journal Arch Pharm Res
Abstract The genus Tamarix in the Tamaricaceae family consists of more than 100 species of halophyte plants worldwide that are mainly used to improve saline-alkali land and for coastal windbreaks, sand fixation, and afforestation in arid areas. A considerable number of species in this genus are also used as traditional medicines to treat various human diseases, especially in Asian and African countries. This review presents a comprehensive summary of 655 naturally occurring compounds derived from the genus Tamarix, categorized into flavonoids (18.0%), phenols (13.9%), tannins (9.3%), terpenoids (10.5%), essential oils (31.0%), and others (17.3%). The investigation revealed that the crude extracts and phytochemicals of this genus exhibited significant therapeutic potential, including anti-inflammatory, anti-Alzheimer, anticancer, antidiabetic, antibacterial, and antifungal activities. Six species of Tamarix have anticancer effects by causing cancer cell death, inducing autophagy, and stopping cell division. Seven species from the same genus have the potential for treating diabetes by inhibiting α-glycosidase activity, suppressing human islet amyloid polypeptide, regulating blood glucose levels, and modulating autophagy or inflammation. The focus on antibacterial and antidiabetic effects is due to the presence of volatile oil and flavonoid components. Extensive research has been conducted on the biological activity of 30 constituents, including 15 flavonoids, 5 phenols, 3 terpenoids, 1 tannin, and 6 others. Therefore, future research should thoroughly study the mechanisms of action of these and similar compounds. This is the most comprehensive review of the phytochemistry and pharmacological properties of Tamarix species, with a critical assessment of the current state of knowledge.
Volume 47(5)
Pages 410-441
Published 2024-5-15
DOI 10.1007/s12272-024-01498-x
PII 10.1007/s12272-024-01498-x
PMID 38750332
MeSH Animals Antineoplastic Agents, Phytogenic / chemistry Antineoplastic Agents, Phytogenic / isolation & purification Antineoplastic Agents, Phytogenic / pharmacology Humans Hypoglycemic Agents / chemistry Hypoglycemic Agents / isolation & purification Hypoglycemic Agents / pharmacology Phytochemicals* / chemistry Phytochemicals* / isolation & purification Phytochemicals* / pharmacology Plant Extracts / chemistry Plant Extracts / isolation & purification Plant Extracts / pharmacology Tamaricaceae* / chemistry
IF 2.934
Resource
GBIF Plant Specimen Database of Tama Forest Science Garden, Forestry and Forest Products Research Institute, Japan Plant specimens of Komatsu City Museum Vascular Plant Specimens of Yamagata Prefectural Museum Herbarium, University Archives and Collections, Fukushima University, Japan (FKSE) Vascular plant specimens of National Museum of Nature and Science (TNS) Herbarium Specimens of Tokushima Prefectural Museum, Japan Vascular Plant Specimens of Kochi Prefectural Makino Botanical Garden Vascular Plant Specimen database of Kanagawa Prefectural Museum of Natural History Vascular Plant Specimens of the RYU Herbarium (Faculty of Science, University of the Ryukyus) Plant specimens of Obihiro Centennial City Museum Vascular plant specimens of Nagano Environmental Conservation Research Institute, Nagano Prefecture