論文 - 詳細
| RRC ID | 82609 |
|---|---|
| 著者 | Rzemieniewski J, Leicher H, Lee HK, Broyart C, Nayem S, Wiese C, Maroschek J, Camgöz Z, Olsson Lalun V, Djordjevic MA, Vlot AC, Hückelhoven R, Santiago J, Stegmann M. |
| タイトル | CEP signaling coordinates plant immunity with nitrogen status. |
| ジャーナル | Nat Commun |
| Abstract |
Plant endogenous signaling peptides shape growth, development and adaptations to biotic and abiotic stress. Here, we identify C-TERMINALLY ENCODED PEPTIDEs (CEPs) as immune-modulatory phytocytokines in Arabidopsis thaliana. Our data reveals that CEPs induce immune outputs and are required to mount resistance against the leaf-infecting bacterial pathogen Pseudomonas syringae pv. tomato. We show that effective immunity requires CEP perception by tissue-specific CEP RECEPTOR 1 (CEPR1) and CEPR2. Moreover, we identify the related RECEPTOR-LIKE KINASE 7 (RLK7) as a CEP4-specific CEP receptor contributing to CEP-mediated immunity, suggesting a complex interplay of multiple CEP ligands and receptors in different tissues during biotic stress. CEPs have a known role in the regulation of root growth and systemic nitrogen (N)-demand signaling. We provide evidence that CEPs and their receptors promote immunity in an N status-dependent manner, suggesting a previously unknown molecular crosstalk between plant nutrition and cell surface immunity. We propose that CEPs and their receptors are central regulators for the adaptation of biotic stress responses to plant-available resources. |
| 巻・号 | 15(1) |
| ページ | 10686 |
| 公開日 | 2024-12-16 |
| DOI | 10.1038/s41467-024-55194-x |
| PII | 10.1038/s41467-024-55194-x |
| PMID | 39681561 |
| PMC | PMC11649690 |
| MeSH | Arabidopsis* / genetics Arabidopsis* / immunology Arabidopsis* / metabolism Arabidopsis* / microbiology Arabidopsis Proteins* / genetics Arabidopsis Proteins* / immunology Arabidopsis Proteins* / metabolism Gene Expression Regulation, Plant Nitrogen* / metabolism Peptides / immunology Peptides / metabolism Plant Diseases* / immunology Plant Diseases* / microbiology Plant Immunity* / genetics Plant Leaves / immunology Plant Leaves / metabolism Plant Leaves / microbiology Plant Roots / immunology Plant Roots / metabolism Plant Roots / microbiology Pseudomonas syringae* Signal Transduction* / immunology Stress, Physiological / immunology |
| IF | 12.121 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | Bluesky |
| 各媒体での言及数の合計 | 17 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| シロイヌナズナ / 植物培養細胞・遺伝子 | psi00232 |