RRC ID 83821
著者 Henderson L, Okuzaki Y, Marcelle C, McGrew MJ, Nishijima KI.
タイトル Avian bioresources for developmental biology: Chicken and quail resources in the United Kingdom, France, and Japan.
ジャーナル Dev Biol
Abstract Biological resources are essential for research using chickens and quails, particularly in the field of developmental biology. Various lines of chickens and quails with naturally occurring genetic mutations and diverse phenotypes have been developed. Recent advancements in genetic modification techniques, such as using DNA transposons to modify cultured primordial germ cells (PGCs) and lentivirus-mediated transduction of PGCs in vivo, have enabled the creation of several transgenic chicken and quail lines. However, the relatively large body size of chickens and the need to maintain living animals due to the previous lack of reliable frozen stock methods, until the development of cultivating methods of PGCs, has caused a steady decline in the number of available lines globally. Several research facilities maintain chicken and quail lines and provide them for research purposes. This review describes the three main avian resource sites: The National Avian Research Facility at The Roslin Institute in the United Kingdom, Lyon Transgenic Quail Facility (MeLiS) in France, and Avian Bioscience Research Center at Nagoya University in Japan.
巻・号 521
ページ 1-13
公開日 2025-5-1
DOI 10.1016/j.ydbio.2025.02.001
PII S0012-1606(25)00031-4
PMID 39904408
MeSH Animals Animals, Genetically Modified* Chickens* / genetics Developmental Biology* France Germ Cells Japan Quail* United Kingdom
IF 2.896
リソース情報
ニワトリ・ウズラ