RRC ID 84241
Author Hayashi D, Kashiwada-Nakamura K, Noguchi H, Matsumoto T, Yaguchi T, Ohara S, Kubo M, Makino K, Fukushima S.
Title Onychomycosis caused by Aspergillus species belonging to section Circumdati.
Journal J Dermatol
Abstract We encountered two cases of onychomycosis caused by Aspergillus (A.) subramanianii and A. sclerotiorum. These species belong to the Aspergillus section Circumdati, which is reportedly common in a wide range of habitats. The members of section Circumdati rarely cause onychomycosis. We report the second and fifth cases of A. subramanianii and A. sclerotiorum in the world. Positive findings in dermatophyte antigen kits helped us to diagnose these infections. These isolates were sensitive to ravuconazole, with a minimum inhibitory concentration of  0.5 μg/mL. They were successfully treated with oral fosravuconazole. We discuss 14 cases of onychomycosis caused by Aspergillus section Circumdati.
Volume 52(3)
Pages 536-540
Published 2025-3-1
DOI 10.1111/1346-8138.17560
PMID 39620628
MeSH Adult Aged Antifungal Agents / pharmacology Antifungal Agents / therapeutic use Aspergillosis* / diagnosis Aspergillosis* / drug therapy Aspergillosis* / microbiology Aspergillus* / drug effects Aspergillus* / isolation & purification Female Foot Dermatoses* / diagnosis Foot Dermatoses* / drug therapy Foot Dermatoses* / microbiology Humans Male Microbial Sensitivity Tests Middle Aged Onychomycosis* / diagnosis Onychomycosis* / drug therapy Onychomycosis* / microbiology Treatment Outcome Triazoles / therapeutic use
IF 3.072
Resource
Pathogenic eukaryotic microorganisms Aspergillus subramanianii IFM 69977, Aspergillus sclerotiorum IFM 69078