論文 - 詳細
| RRC ID | 84292 |
|---|---|
| 著者 | Noritake A, Isoda M. |
| タイトル | The macaque medial prefrontal cortex simultaneously represents self and others' reward prediction error. |
| ジャーナル | Cell Rep |
| Abstract |
Learning the causal structures of social environments involves predicting significant events (e.g., rewards) and detecting prediction errors for each agent. Whether the brain can simultaneously compute reward prediction errors for self (S-RPE) and others (O-RPE), and which neurons are responsible, is unclear. Here, we condition two monkeys with identical visual stimuli predicting different reward outcomes and find that dorsomedial prefrontal neurons represent both S-RPE and O-RPE simultaneously. Neuronal signatures of RPE are agent and sign specific, forming distinct populations for positive and negative S-RPE and O-RPE. A linear decoder trained on neurons encoding O-RPE, but not S-RPE, successfully discriminates RPE. Further investigation identifies coexisting actual reward and prediction confirmation signals for others. These results highlight the presence of neuronal mechanisms in the primate brain that update the value of environmental stimuli simultaneously for oneself and others, enabling primates to comprehend the causal structure of the world from the perspective of others. |
| 巻・号 | 44(3) |
| ページ | 115368 |
| 公開日 | 2025-3-25 |
| DOI | 10.1016/j.celrep.2025.115368 |
| PII | S2211-1247(25)00139-1 |
| PMID | 40022727 |
| MeSH | Animals Learning / physiology Macaca mulatta Male Neurons / physiology Photic Stimulation Prefrontal Cortex* / physiology Reward* |
| IF | 8.109 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 6 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| ニホンザル | |