Reference - Detail
| RRC ID | 84294 |
|---|---|
| Author | Chen H, Kunimatsu J, Oya T, Imaizumi Y, Hori Y, Matsumoto M, Tsubo Y, Hikosaka O, Minamimoto T, Naya Y, Yamada H. |
| Title | Formation of brain-wide neural geometry during visual item recognition in monkeys. |
| Journal | iScience |
| Abstract |
Neural dynamics are thought to reflect computations that relay and transform information in the brain. Previous studies have identified the neural population dynamics in many individual brain regions as a trajectory geometry, preserving a common computational motif. However, whether these populations share particular geometric patterns across brain-wide neural populations remains unclear. Here, by mapping neural dynamics widely across temporal/frontal/limbic regions in the cortical and subcortical structures of monkeys, we show that 10 neural populations, including 2,500 neurons, propagate visual item information in a stochastic manner. We found that visual inputs predominantly evoked rotational dynamics in the higher-order visual area, TE, and its downstream striatum tail, while curvy/straight dynamics appeared frequently downstream in the orbitofrontal/hippocampal network. These geometric changes were not deterministic but rather stochastic according to their respective emergence rates. Our meta-analysis results indicate that visual information propagates as a heterogeneous mixture of stochastic neural population signals in the brain. |
| Volume | 28(3) |
| Pages | 111936 |
| Published | 2025-3-21 |
| DOI | 10.1016/j.isci.2025.111936 |
| PII | S2589-0042(25)00196-8 |
| PMID | 40034850 |
| PMC | PMC11875189 |
| IF | 4.447 |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | News |
| Total number of mentions | 14 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Japanese macaques | |