| RRC ID |
84893
|
| 著者 |
Katayama T, Nobu MK, Imachi H, Hosogi N, Meng XY, Morinaga K, Yoshioka H, Takahashi HA, Kamagata Y, Tamaki H.
|
| タイトル |
A Marine Group A isolate relies on other growing bacteria for cell wall formation.
|
| ジャーナル |
Nat Microbiol
|
| Abstract |
Most of Earth's prokaryotes live under energy limitation, yet the full breadth of strategies that enable survival under such conditions remain poorly understood. Here we report the isolation of a bacterial strain, IA91, belonging to the candidate phylum Marine Group A (SAR406 or 'Candidatus Marinimicrobia') that is unable to synthesize the central cell wall compound peptidoglycan itself. Using cultivation experiments and microscopy, we show that IA91 growth and cell shape depend on other bacteria, deriving peptidoglycan, energy and carbon from exogenous muropeptide cell wall fragments released from growing bacteria. Reliance on exogenous muropeptides is traceable to the phylum's ancestor, with evidence of vertical inheritance across several classes. This dependency may be widespread across bacteria (16 phyla) based on the absence of key peptidoglycan synthesis genes. These results suggest that uptake of exogenous cell wall components could be a relevant and potentially common survival strategy in energy-limited habitats like the deep biosphere.
|
| 巻・号 |
9(8)
|
| ページ |
1954-1963
|
| 公開日 |
2024-8-1
|
| DOI |
10.1038/s41564-024-01717-7
|
| PII |
10.1038/s41564-024-01717-7
|
| PMID |
38831032
|
| MeSH |
Aquatic Organisms
Bacteria* / classification
Bacteria* / genetics
Bacteria* / isolation & purification
Bacteria* / metabolism
Carbon / metabolism
Cell Wall* / metabolism
Energy Metabolism
Peptidoglycan* / metabolism
Phylogeny
Seawater / microbiology
|
| リソース情報 |
| 一般微生物 |
JCM39386
JCM39387 |
